This mystery is profound, and I am saying that it refers to Christ and the church.
Eternal Word Television Network, "What Catholics Really Believe: Setting the Record Straight" (1992 Karl Keating), which contains 52 chapters, each devoted to a common misconception about the Catholic faith. The book is available from Catholic Answers
"Fundamentalists, and even some Catholics, are surprised to learn that celibacy has not been a rule for all Catholic priests. In the early centuries priests and bishops could be married—the practices in the West and East were the same—but celibacy was soon preferred, and eventually it became mandatory. By the early Middle Ages, the rule of celibacy, in the Latin or Western Rite, was firmly in place."
In the 1330s a large number of natural disasters and plagues led to widespread famine, starting in 1331, with a deadly plague arriving soon after. Epidemics which may have included plague killed an estimated 25 million Chinese and other Asians during the 15 years before it reached Constantinople in 1347.
Within, roughly, a hundred years, Martin Luther was to be born.
Mask of Martin Luther and his hands, age 62